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Dosing Cycle▾  |   How to Administer

Convenient dosing and administration

ZIEXTENZO is administered once per cycle as a subcutaneous injection, following the same dosing schedule and route of administration as Neulasta®1,2

ZIEXTENZO 6 mg/0.6 mL prefilled syringe.

Convenient, once-per-cycle dosing is the same as Neulasta® (pegfilgrastim)1,2

  ZIEXTENZO
Indication
  • ZIEXTENZO is indicated to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia1

Limitations of Use

ZIEXTENZO is not indicated for the mobilization of peripheral blood progenitor cells for hematopoietic stem cell transplantation.1

Dosage forms

Injection: 6 mg/0.6 mL prefilled syringe1

Active ingredient

Pegfilgrastim-bmez1

Administration

ZIEXTENZO is administered as a single-dose subcutaneous injection once per chemotherapy cycle.1

  • ZIEXTENZO is supplied as a 6 mg/0.6 mL solution in a single-dose prefilled syringe for manual subcutaneous injection (NDC 61314-866-01)1
  • It is available with a BD™ UltraSafe Passive® Needle Guard that provides one-handed passive activation1,3
  • Do not administer ZIEXTENZO between 14 days before and 24 hours after administration of cytotoxic chemotherapy1

In-home administration is another option for your ZIEXTENZO patients

For patients who cannot make their injection appointments, see how ZIEXTENZO can be self-administered or administered by a caregiver.

Self-administering ZIEXTENZO

Administering ZIEXTENZO as a caregiver

BD is a trademark of Becton, Dickinson and Company. UltraSafe Passive is a registered trademark of Safety Syringes, Inc.
Neulasta is a registered trademark of Amgen Inc.

References: 1. ZIEXTENZO Prescribing Information. Sandoz Inc. March 2021. 2. Neulasta Prescribing Information. Amgen Inc. March 2021. 3. BD safety and shielding systems. BD Drug Delivery Systems website. https://drugdeliverysystems.bd.com/products/safety-and-shielding-systems/ultrasafe-passive-needle-guard. Accessed May 24, 2023.